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A study involving 173 Danish women who under went screening mammographys between the eyars of 1993 and 2007 yielded some interesting results. They found that those that used hormones had more false-positve results than women who never used hormone replacement therapy. They found that of 39, 104 women who took the hormone replacement therapy that 602 had false positve results, and they needed further testing. The remaining, 0.8 percent of the 133, 638 women had nver used hormone therapy. If you used patches, and injections the women had twice the false postive risk.

This was quite an interesting study. More research needs to be done to see what hormones are safest and don’t result in false positive results.

Hormone replalcement therapy increases breast density. As women get older, typically their breast tissue will be less dense and more fatty. That is not always the case.  Younger women have more breast density. I wonder if it could be due to al their hormones. Sounds like something I said years ago. I still say they need to reduce hormones in our diet, hormone free meat, minicing hormones, etc.

If you stop hormone replacement therapy, your risk of a false positive mammogram should go down. In the United States in 2008 they found that women who had been on oral HRT for five years, the odds of their having an inaccurate mammogram declined after women stop taking the hormones. Now this doesn’t seem to go with women more at risk for breast cancer as they age, does it?

Some women take hormone replacement therapy until they die. They feel it has helped them, inspite of the risk. These women take it to reduce their menopausal symptoms. For relatives it was hot flashes, etc.



According to the American Cancer Society’s chart on BC Incident and Mortality Rates by Race and State (2002-2006), Minnesota will have 126.4 (White/Caucasian)  as their incident rate. (All rates are per 100,00 and age adjusted to the 2000 US standard population.) The mortality rate for Minnesota is 22.3 for White/Caucasian.

The African American incident rate is 121.1 but the African American mortality rate is 36.8 for Minnesota. As you can see African American women have a lot higher mortality rate and yet the money raised doesn’t seem to head their way.

It seems to be heading toward white Causian women.



Some people volunteer to help others and others are seeking donations for their salaries. It may seem like they really to help others. Ask the breast cancer patients involved in the community. Someone came up to me asked me about a group that raises money and only one person gets the money. I said, ” No, I am strictly a volunteer as is ever one else that I am involved with.”



{March 22, 2010}   What is This?

I saw a poster at the Duluth Grill,  and it was about HOTDISH Militia c/o WHC 32 E. lst Street, Duluth, MN 55802.  Isn’t that the building for women that the YWCA owns?  I wouldn’t of noticed the pot luck at Peace Church which read Lutheran Ladies hotdish, etc. but it talked about young women.  I pulled off a tab, googled it, and it is about abortion, gays, lesbians, etc. Chances are that the Duluth Grill doesn’t know what kind of poster they hung up or how hot of a topic this is in our community.

http://www.hotdishmilitia.org/

www.pamelameans.com/

E-mail: hotdishmilitia@gmail.com

The Lutherans are not gun hoe about abortions and for sure Lutheran Ladies are not.  Who ever thought that one up? We have friends who are anti-abortion.  This is a hot topic with this doctor and his wife.  I don’t understand why the Peace Church is sponsoring it. Maybe Building for Women, non-profit members or owners are part of the group.



{March 19, 2010}   Breast Cancer is Big Money

Breast Cancer is big money.  We just need to ask how it is being used, where it is going, and if we can see the use.  When there is not transparency, it is a wasted cause. Some folks use it for salaries, others use it for their own benefit, not the patient.  Ask, ask, ask, and ask some more.  Ask to see where it is going on paper.



RN Nurses are working 8-12 hour shifts at the hospital.  It makes one wonder when they have up to 26 patients on a floor, 2 nurses, sometimes 3, working long shifts, if this is safe for the patient and for them. Last year a nurse drove home from SMDC, tired from two shifts, fell asleep at the wheel, and was killed.

A study found that 3% of all women who worked nights got breast cancer.  This was probably from low melatoin levels.  Shift work has its problems with womens health.



{March 14, 2010}   Uterine Fibroids

Uterine fibroids are more common or we hear about them more nowdays.  They are often benign tumors found in 80% of women.  They can be caused from genetics or even birth control pills.  It seems that many African American women get them.

Fibroids can cause heavy bleeding, anemia, pain, pressure, bowel urgency problems, and sexual intercourse problems.



Sporadic breast cancer is breast cancer that is not inherited. We don’t know if the environment plays a role in these cases, at least, not yet.

Hereditary breast cancer is from inherited gene mutations, occurs eariler in life, and involves both breasts.  This makes up 5-10 percent of all breast cancers.  It’s common with people of Ashkenazi Jewish heritages, Norwegian people, Icelandic or Dutch ancestry. The types are BRCA1, BRCA2, and there are many other genes they have identified. Some are somanic mutations and some are inherited. Men can get breast cancer too, it is the incident rate  with young women. Young African American women are at risk.



{March 2, 2010}   Estradiol in Breast Cancer

There is a book called Advances in Experiemental Medicine and Biology, Innovative Endocrinology of Cancer by Leve M Berstein and Richard J. Santeen, ISSN 0065-2598.

This book talks about the adaptation of estradiol causing regulation of growth factor pathways and hypersensitivity to estradiol in breast cancer.  Women relapse after treatment. Researcher, Richard Santeen has abrogated the growth factor induced hypersensitivity by utilizing a drug called farnesylthiosalicylic acid that blocks the binding of the GTP-Ras to its membrance acceptor protein, galectin 1 and reduced the activation of the MAP kinase. 

Patients are relapsing from Tamoxifen due to the growth factor pathways and this hypersensitivity can be changed or reversed.  I wonder how this research is progressing?  Is it being  used to save lives?



{February 17, 2010}   DCIS, What’s The True Scoop?

A book called Should I Be Tested For Cancer states in the notes, “While breast cancer is less common in younger women, the problem of pseudodisease is actually more common.  the panel did not qualify the problem of pseudodisease because that’s hard to do. They say that one of every eight biopsies in this age group is read as DCIS, the diagnosis most likley to be pseudodisease. The biopsy rate varies depending on who reads the mammograms.  But a ball park estimate is that for every 1,000, 40 year old women screened over 10 years, somewhere between 10-20  will be diagnosed with breast cancer unnecessarily.”



et cetera